Hydrogenation of butane-2,3-dione with heterogeneous cinchona modified platinum catalysts: a combination of an enantioselective reaction and kinetic resolution

被引：53

作者：

Studer, M ^{[1
]}

Okafor, V

Blaser, HU

机构：

[1] Novartis Serv AG, Sci Serv, CH-4002 Basel, Switzerland

[2] Univ Witwatersrand, Dept Chem, Johannesburg, South Africa

来源：

CHEMICAL COMMUNICATIONS | 1998年 / 09期

关键词：

D O I：

10.1039/a801390j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(R)-3-Hydroxybutan-2-one was obtained with 85-90% ee albeit in low yield by the Pt/Al2O3 cinchona catalyzed hydrogenation of butane-2,3-dione by a combination of enantioselective hydrogenation and kinetic resolution.

引用

页码：1053 / 1054

页数：2

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