Line tension at fluid membrane domain boundaries measured by micropipette aspiration

被引：134

作者：

Tian, Aiwei ^{[1
]}

Johnson, Corinne ^{[1
]}

Wang, Wendy ^{[1
]}

Baumgart, Tobias ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Philadelphia, PA 19104 USA

来源：

PHYSICAL REVIEW LETTERS | 2007年 / 98卷 / 20期

关键词：

D O I：

10.1103/PhysRevLett.98.208102

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Line tension is a determinant of fluid phase domain formation kinetics and morphology in lipid bilayer membranes, which are models for biological membrane heterogeneity. We describe the first direct measurement of this line tension by micropipette aspiration. Our data are analyzed with a model that does not rely on independently measured (and composition dependent) secondary parameters, such as bending stiffness or membrane viscosities. Line tension is strongly composition dependent and decreases towards a critical consolute point in a quasiternary room temperature phase diagram.

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页数：4

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