The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease

被引：26

作者：

Blevins, JS

Revel, AT

Caimano, MJ

Yang, XFF

Richardson, JA

Hagman, KE

Norgard, MV

机构：

[1] Univ Texas, SW Med Ctr, Dept Microbiol, Dallas, TX 75390 USA

[2] Univ Texas, SW Med Ctr, Dept Pathol, Dallas, TX 75390 USA

[3] Univ Connecticut, Ctr Hlth, Dept Pathol, Farmington, CT 06030 USA

[4] Univ Connecticut, Ctr Hlth, Ctr Microbial Pathogenesis, Farmington, CT 06030 USA

来源：

INFECTION AND IMMUNITY | 2004年 / 72卷 / 08期

关键词：

D O I：

10.1128/IAI.72.8.4864-4867.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

luxS mutants of Borrelia burgdorferi strain 297 naturally colonized their arthropod (Rodes scapularis) vector, were maintained in ticks throughout the molting process (larvae to nymphs), were tick transmitted to uninfected mice, and elicited histopathology in mice indistinguishable from that induced by wild-type B. burgdorferi.

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收藏

页码：4864 / 4867

页数：4

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