Cardiac neurotransmission SPECT imaging

被引：52

作者：

Flotats, A ^{[1
]}

Carrió, I ^{[1
]}

机构：

[1] Hosp Santa Creu & Sant Pau, Dept Nucl Med, E-08025 Barcelona, Spain

来源：

JOURNAL OF NUCLEAR CARDIOLOGY | 2004年 / 11卷 / 05期

关键词：

cardiac sympathetic innervation; single photon emission computed tomography; iodine; 123; metaiodobenzylguanidine;

D O I：

10.1016/j.nuclcard.2004.07.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The sympathetic nervous system has great influence on cardiovascular physiology. Cardiac neurotransmission single photon emission computed tomography (SPECT) imaging allows in vivo noninvasive assessment of presynaptic reuptake and storage of neurotransmitters, which offers characterization of the cardiac neuronal function in different diseases of the heart and other altered metabolic or functional conditions. Therefore assessment of the integrity of cardiac sympathetic innervation may help in the diagnosis of these disorders, as well as in prognostication, and will result in better therapy and outcome. At present, the most widely available SPECT tracer by which to assess cardiac neurotransmission is metaiodobenzylguanidine labeled with iodine 123. This article focuses on reviewing the characteristics of cardiac SPECT imaging with I-1.23 metaiodobenzylguanidine and its role in the assessment of pathophysiologic changes during relevant clinical conditions.

引用

页码：587 / 602

页数：16

共 105 条

[1] Impact of exercise rehabilitation on cardiac neuronal function in heart failure: an iodine-123 metaiodobenzylguanidine scintigraphy study [J].

Agostini, D ;

Lecluse, E ;

Belin, A ;

Babatasi, G ;

Amar, MH ;

Grollier, G ;

Potier, JC ;

Bouvard, G .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 1998, 25 (03) :235-241

[2]

Agostini D, 2000, J NUCL MED, V41, P845

[3] I-123 MIBG imaging and heart rate variability analysis to predict the need for an implantable cardioverter defibrillator [J].

Arora, R ;

Ferrick, KJ ;

Nakata, T ;

Kaplan, RC ;

Rozengarten, M ;

Latif, F ;

Ng, K ;

Marcano, V ;

Heller, S ;

Fisher, JD ;

Travin, MI .

JOURNAL OF NUCLEAR CARDIOLOGY, 2003, 10 (02) :121-131

[4] Arrhythmogenic right ventricular cardiomyopathy - Dysplasia, dystrophy, or myocarditis? [J].

Basso, C ;

Thiene, G ;

Corrado, D ;

Angelini, A ;

Nava, A ;

Valente, M .

CIRCULATION, 1996, 94 (05) :983-991

[5]

BELLAVERE F, 1988, BRIT HEART J, V59, P379

[6] Expanding indications for implantable cardiac defibrillators [J].

Bigger, JT .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (12) :931-933

[7] Cardiac uptake of [123I]MIBG separates Parkinson's disease from multiple system atrophy [J].

Braune, S ;

Reinhardt, M ;

Schnitzer, R ;

Riedel, A ;

Lücking, CH .

NEUROLOGY, 1999, 53 (05) :1020-1025

[8] The role of cardiac metaiodobenzylguanidine uptake in the differential diagnosis of parkinsonian syndromes [J].

Braune, S .

CLINICAL AUTONOMIC RESEARCH, 2001, 11 (06) :351-355

[9] RIGHT BUNDLE-BRANCH BLOCK, PERSISTENT ST SEGMENT ELEVATION AND SUDDEN CARDIAC DEATH - A DISTINCT CLINICAL AND ELECTROCARDIOGRAPHIC SYNDROME - A MULTICENTER REPORT [J].

BRUGADA, P ;

BRUGADA, J .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1992, 20 (06) :1391-1396

[10]

Carrió I, 2001, J NUCL MED, V42, P1062

← 1 2 3 4 5 6 7 8 9 10 →