The role of the right inferior frontal gyrus: inhibition and attentional control

被引：1009

作者：

Hampshire, Adam ^{[1
]}

Chamberlain, Samuel R. ^{[2
]}

Monti, Martin M. ^{[1
]}

Duncan, John ^{[1
]}

Owen, Adrian M. ^{[1
]}

机构：

[1] MRC, Cognit & Brain Sci Unit, Cambridge, England

[2] Univ Cambridge, Addenbrookes Hosp, Dept Psychiat, Sch Clin Med, Cambridge CB2 2QQ, England

来源：

NEUROIMAGE | 2010年 / 50卷 / 03期

基金：

英国医学研究理事会;

关键词：

RESPONSE-INHIBITION; PREFRONTAL CORTEX; TARGET DETECTION; MOTOR CONTROL; TASK; ACTIVATION; THOUGHT; MODEL; MECHANISMS; SPACE;

D O I：

10.1016/j.neuroimage.2009.12.109

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

There is growing interest regarding the role of the right inferior frontal gyrus (RIFG) during a particular form of executive control referred to as response inhibition. However, tasks used to examine neural activity at the point of response inhibition have rarely controlled for the potentially confounding effects of attentional demand. In particular, it is unclear whether the RIFG is specifically involved in inhibitory control, or is involved more generally in the detection of salient or task relevant cues. The current fMRI study sought to clarify the role of the RIFG in executive control by holding the stimulus conditions of one of the most popular response inhibition tasks-the Stop Signal Task-constant, whilst varying the response that was required on reception of the stop signal cue. Our results reveal that the RIFG is recruited when important cues are detected, regardless of whether that detection is followed by the inhibition of a motor response, the generation of a motor response, or no external response at all. (C) 2010 Elsevier Inc. All rights reserved.

引用

页码：1313 / 1319

页数：7

共 58 条

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