Sorting out the multiple roles of Fas ligand

被引：16

作者：

Bossi, G

Stinchcombe, JC

Page, LJ

Griffiths, GM

机构：

[1] Univ Oxford, Sir William Dunn Sch Pathol, Oxford OX1 3RE, England

[2] Imperial Canc Res Fund, Labs, London WC2A 3PX, England

来源：

EUROPEAN JOURNAL OF CELL BIOLOGY | 2000年 / 79卷 / 08期

基金：

英国惠康基金;

关键词：

Fas ligand (CD95 ligand); cytotoxic T lymphocyte; sorting; secretory lysosome;

D O I：

10.1078/0171-9335-00077

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Fas ligand can both be used by the immune system to initiate cell death, and be used by non-lymphoid cells to evade death. Recent work has shown that Fas ligand is differentially sorted in different cell type!;. Here we present the viewpoint that the differential sorting prays an important part in determining the role of Fas ligand in different cells.

引用

页码：539 / 543

页数：5

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