Cross-Neutralization between Human and African Bat Mumps Viruses

被引:16
作者
Katoh, Hiroshi [1 ]
Kubota, Toru [1 ]
Ihara, Toshiaki [2 ]
Maeda, Ken [3 ]
Takeda, Makoto [1 ]
Kidokoro, Minoru [1 ]
机构
[1] Natl Inst Infect Dis, Tokyo, Japan
[2] Mie Hosp, Tsu, Mie, Japan
[3] Yamaguchi Univ, Yamaguchi, Japan
关键词
FUSION; OUTBREAK;
D O I
10.3201/eid2204.151116
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans.
引用
收藏
页码:703 / 706
页数:4
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