How Do Scores on the ADAS-Cog, MMSE, and CDR-SOB Correspond?

被引:99
作者
Balsis, Steve [1 ]
Benge, Jared F. [2 ]
Lowe, Deborah A. [1 ]
Geraci, Lisa [1 ]
Doody, Rachelle S. [3 ]
机构
[1] Texas A&M Univ, Dept Psychol, Mailstop 4235, College Stn, TX 77843 USA
[2] Baylor Scott & White Hlth, Dept Neurol, Temple, TX USA
[3] Baylor Coll Med, Dept Neurol, Alzheimers Dis & Memory Disorders Ctr, Houston, TX 77030 USA
关键词
ADAS; Alzheimer's disease; CDR; Dementia; IRT; MCI; MMSE; Psychometric; Neuropsychological assessment; ALZHEIMERS-DISEASE; RATING-SCALE; DEMENTIA; STATE;
D O I
10.1080/13854046.2015.1119312
中图分类号
B849 [应用心理学];
学科分类号
040203 [应用心理学];
摘要
Objective: Clinicians and researchers who measure cognitive dysfunction often use the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog), the Mini-Mental State Examination (MMSE), or the Clinical Dementia Rating scale (CDR-SOB). But, the use of different measures can make it difficult to compare data across patients or studies. What is needed is a simple chart that shows how scores on these three important measures correspond to each other. Methods: Using data from 1709 participants from the Alzheimer's Disease Neuroimaging Initiative and item response theory-based statistics, we analyzed how scores on each measure, the ADAS-Cog, the MMSE, and the CDR-SOB, correspond. Results: Results indicated multiple inflections in CDR-SOB and ADAS-Cog scores within a given MMSE score, suggesting that the CDR-SOB and ADAS-Cog are more precise in measuring the severity of cognitive dysfunction than the MMSE. Conclusions: This study shows how scores on these three popular measures of cognitive dysfunction correspond to each other, which is very useful information for both researchers and clinicians.
引用
收藏
页码:1002 / 1009
页数:8
相关论文
共 16 条
[1]
Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study) [J].
Aisen, Paul S. ;
Gauthier, Serge ;
Ferris, Steven H. ;
Saumier, Daniel ;
Haine, Denis ;
Garceau, Denis ;
Anh Duong ;
Suhy, Joyce ;
Oh, Joonmi ;
Lau, Wan C. ;
Sampalis, John .
ARCHIVES OF MEDICAL SCIENCE, 2011, 7 (01) :102-111
[2]
[Anonymous], 2000, ITEM RESPONSE THEORY
[3]
[Anonymous], 1969, PSYCHOMETRIC MONOGRA
[4]
Evaluating goodness-of-fit indexes for testing measurement invariance [J].
Cheung, GW ;
Rensvold, RB .
STRUCTURAL EQUATION MODELING-A MULTIDISCIPLINARY JOURNAL, 2002, 9 (02) :233-255
[5]
Changing patient characteristics and survival experience in an Alzheimer's center patient cohort [J].
Doody, R ;
Pavlik, V ;
Massman, P ;
Kenan, M ;
Yeh, S ;
Powell, S ;
Cooke, N ;
Dyer, C ;
Demirovic, J ;
Waring, S ;
Chan, WY .
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2005, 20 (2-3) :198-208
[6]
MINI-MENTAL STATE - PRACTICAL METHOD FOR GRADING COGNITIVE STATE OF PATIENTS FOR CLINICIAN [J].
FOLSTEIN, MF ;
FOLSTEIN, SE ;
MCHUGH, PR .
JOURNAL OF PSYCHIATRIC RESEARCH, 1975, 12 (03) :189-198
[7]
Hambleton R. K., 1991, Fundamentals of a Item Responde Theory
[8]
A NEW CLINICAL-SCALE FOR THE STAGING OF DEMENTIA [J].
HUGHES, CP ;
BERG, L ;
DANZIGER, WL ;
COBEN, LA ;
MARTIN, RL .
BRITISH JOURNAL OF PSYCHIATRY, 1982, 140 (JUN) :566-572
[9]
MCKHANN G, 1984, NEUROLOGY, V34, P939, DOI 10.1212/WNL.34.7.939
[10]
Advanced Dementia: State of the Art and Priorities for the Next Decade [J].
Mitchell, Susan L. ;
Black, Betty S. ;
Ersek, Mary ;
Hanson, Laura C. ;
Miller, Susan C. ;
Sachs, Greg A. ;
Teno, Joan M. ;
Morrison, R. Sean .
ANNALS OF INTERNAL MEDICINE, 2012, 156 (01) :45-U95