Dendritic BINAP based system for asymmetric hydrogenation of simple aryl ketones

被引：35

作者：

Deng, GJ

Fan, QH

Chen, XM

Liu, GH

机构：

[1] Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China

[2] Nankai Univ, State Key Lab Elemental Organ Chem, Tianjin 300071, Peoples R China

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2003年 / 193卷 / 1-2期

基金：

中国国家自然科学基金;

关键词：

asymmetric hydrogenation; dendritic catalyst; BINAP; DPEN; chiral secondary alcohol; POLYMER-SUPPORTED CATALYSTS; STEREOSELECTIVE HYDROGENATION; LIGANDS;

D O I：

10.1016/S1381-1169(02)00452-1

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A series of dendritic BINAP-Ru/chiral diamine catalysts were developed for asymmetric hydrogenation of various simple aryl ketones. The resulting catalytic system showed very attractive due to very good catalytic activity and enantioselectivity as well as facile catalyst recycling. In the case of 1-acetonaphthone and 2'-methyl-acetophenone, interesting e.e. value up to 95% was observed which are comparable to the enantioselectivity reported by Noyori under similar conditions and higher than that of the heterogeneous poly(BINAP)-Ru catalyst reported by Pu and co-workers [Tetrahedron Lett. 41 (2000) 1681]. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：21 / 25

页数：5

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