Two polyisoprenylated benzophenones from the trunk latex of Clusia grandiflora (Clusiaceae)

被引：60

作者：

Lokvam, J ^{[1
]}

Braddock, JF

Reichardt, PB

Clausen, TP

机构：

[1] Univ Alaska Fairbanks, Dept Biol & Wildlife, Fairbanks, AK 99775 USA

[2] Univ Alaska Fairbanks, Off Provost, Fairbanks, AK 99775 USA

[3] Univ Alaska Fairbanks, Dept Chem & Biochem, Fairbanks, AK 99775 USA

来源：

PHYTOCHEMISTRY | 2000年 / 55卷 / 01期

基金：

美国国家科学基金会;

关键词：

Clusia grandiflora; Clusiaceae; benzophenone; nemorosone II; chamone I; chamone II; antibacterial pollinator reward; antibacterial latex; pollinator reward evolution;

D O I：

10.1016/S0031-9422(00)00193-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The polyisoprenylated benzophenones, chamones I and II, were isolated from the trunk latex of Clusia glandiflora (Clusiaceae) growing in southeastern Venezuela. A third benzophenone, nemorosone II, was isolated from the pollinator reward resin of the female flowers of the same plant. Chamone I and nemorosone II are structurally similar, differing only in the degree of prenylation. Bioassays of chamone I and nemorosone II using the honeybee pathogens, Paenibacillus larvae and Paenibacillus alvei, demonstrate that both have potent antibacterial activity, and that their structural differences affect both their bactericidal efficacies and their aqueous mobilities. (C) 2000 Elsevier Science Ltd. AII rights reserved.

引用

页码：29 / 34

页数：6

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