Recent Advances from the National Cancer Institute Alliance for Nanotechnology in Cancer

被引:56
作者
Farrell, Dorothy [1 ]
Alper, Joe [2 ]
Ptak, Krzystof [1 ]
Panaro, Nicholas J. [3 ]
Grodzinski, Piotr [1 ]
Barker, Anna D. [4 ]
机构
[1] NCI, Ctr Strateg Sci Initiat, Bethesda, MD 20892 USA
[2] Parrotfish Consulting, Louisville, CO 80027 USA
[3] NCI, Nanotechnol Characterizat Lab, Adv Technol Program, SAIC Frederick Inc, Frederick, MD 21702 USA
[4] NCI, Off Director, Bethesda, MD 20892 USA
基金
美国国家卫生研究院;
关键词
CELL-PENETRATING PEPTIDES; TUMOR-CELLS; NANOPARTICLES; NANOPYRAMIDS; DELIVERY; PLATFORM;
D O I
10.1021/nn100073g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Nanotechnology will have great impact on how cancer is diagnosed and treated in the future. New technologies to detect and image cancerous changes and materials that enable new methods of cancer treatment will radically alter patient outcomes. The National Cancer Institute (NCI) Alliance for Nanotechnology in Cancer sponsors research in cancer prevention, diagnosis, and therapy and promotes translation of basic science discoveries into clinical practice. The Fourth Annual NCI Alliance Principal Investigator Meeting was held in Manhattan Beach, California October 20-22, 2009. Presented here are highlights from the research presentations at the meeting, in the areas of in vitro diagnostics, targeted delivery of anticancer and contrast enhancement agents, and nanotherapeutics and therapeutic monitoring.
引用
收藏
页码:589 / 594
页数:6
相关论文
共 17 条
[1]   DNA-encoded antibody libraries: A unified platform for multiplexed cell sorting and detection of genes and proteins [J].
Bailey, Ryan C. ;
Kwong, Gabriel A. ;
Radu, Caius G. ;
Witte, Owen N. ;
Heath, James R. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (07) :1959-1967
[2]   Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles [J].
Bartlett, Derek W. ;
Davis, Mark E. .
BIOCONJUGATE CHEMISTRY, 2007, 18 (02) :456-468
[3]   In vivo optical molecular imaging of vascular endothelial growth factor for monitoring cancer treatment [J].
Chang, Sung K. ;
Rizvi, Imran ;
Solban, Nicolas ;
Hasan, Tayyaba .
CLINICAL CANCER RESEARCH, 2008, 14 (13) :4146-4153
[4]  
FANG R, 2008, NAT BIOTECHNOL, V26, P1373
[5]   Cancer nanotechnology: Opportunities and challenges [J].
Ferrari, M .
NATURE REVIEWS CANCER, 2005, 5 (03) :161-171
[6]   Selective functionalization and spectral identification of gold nanopyramids [J].
Hasan, Warefta ;
Lee, Jeunghoon ;
Henzie, Joel ;
Odom, Teri W. .
JOURNAL OF PHYSICAL CHEMISTRY C, 2007, 111 (46) :17176-17179
[7]   Tailoring the Structure of Nanopyramids for Optimal Heat Generation [J].
Hasan, Warefta ;
Stender, Christopher L. ;
Lee, Min Hyung ;
Nehl, Colleen L. ;
Lee, Jeunghoon ;
Odom, Teri W. .
NANO LETTERS, 2009, 9 (04) :1555-1558
[8]   Tumor imaging by means of proteolytic activation of cell-penetrating peptides [J].
Jiang, T ;
Olson, ES ;
Nguyen, QT ;
Roy, M ;
Jennings, PA ;
Tsien, RY .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (51) :17867-17872
[9]   Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells [J].
Kwong, Gabriel A. ;
Radu, Caius G. ;
Hwang, Kiwook ;
Shu, Chengyi J. ;
Ma, Chao ;
Koya, Richard C. ;
Comin-Anduix, Begonya ;
Hadrup, Sine Reker ;
Bailey, Ryan C. ;
Witte, Owen N. ;
Schumacher, Ton N. ;
Ribas, Antoni ;
Heath, James R. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (28) :9695-9703
[10]   Pyramids: A Platform for Designing Multifunctional Plasmonic Particles [J].
Lee, Jeunghoon ;
Hasan, Warefta ;
Stender, Christopher L. ;
Odom, Teri W. .
ACCOUNTS OF CHEMICAL RESEARCH, 2008, 41 (12) :1762-1771