Altered regional blood flow in the fetus: the origins of cardiovascular disease?

被引:27
作者
Barker, DJP [1 ]
Hanson, MA [1 ]
机构
[1] Univ Southampton, MRC, Environm Epidemiol Unit, Div Dev Origins Adult Hlth & Dis, Southampton, Hants, England
关键词
fetal blood flow; intrauterine growth retardation; cardiovascular disease;
D O I
10.1080/08035250410024772
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
A fetal response to hypoxia and other adverse influences is to redistribute blood flow in order to "spare" the brain. This, however, is associated with reduced growth of the liver and kidneys. Conclusion: The long-term consequences of fetal redistribution of blood flow are unknown, but preliminary evidence suggests that there is an increased risk of coronary heart disease and hypertension in later life.
引用
收藏
页码:1559 / 1560
页数:2
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