Are linkage analysis and the collection of family data dead? Prospects for family studies in the age of genome-wide association

被引:38
作者
Clerget-Darpoux, Francoise
Elston, Robert C.
机构
[1] Hop Paul Brousse, INSERM U535, Genet Epidemiol & Struct Populat Humaines, F-94817 Villejuif, France
[2] Univ Paris Sud, IRF69, UMR S535, Villejuif, France
[3] Case Western Reserve Univ, Cleveland, OH 44106 USA
关键词
D O I
10.1159/000101960
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:91 / 96
页数:6
相关论文
共 39 条
[1]   Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort [J].
Amundsen, SS ;
Monsuur, AJ ;
Wapenaar, MC ;
Lie, BA ;
Ek, J ;
Gudjónsdóttir, AH ;
Ascher, H ;
Wijmenga, C ;
Sollid, LM .
HUMAN IMMUNOLOGY, 2006, 67 (4-5) :341-345
[2]   A POLYMORPHIC LOCUS NEAR THE HUMAN INSULIN GENE IS ASSOCIATED WITH INSULIN-DEPENDENT DIABETES-MELLITUS [J].
BELL, GI ;
HORITA, S ;
KARAM, JH .
DIABETES, 1984, 33 (02) :176-183
[3]  
BOURGEY M, IN PRESS GUT
[4]   A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: Report of the birth defects research group [J].
Brody, LC ;
Conley, M ;
Cox, C ;
Kirke, PN ;
McKeever, MP ;
Mills, JL ;
Molloy, AM ;
O'Leary, VB ;
Parle-McDermott, A ;
Scott, JM ;
Swanson, DA .
AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (05) :1207-1215
[5]   Powerful multilocus tests of genetic association in the presence of gene-gene and gene-environment interactions [J].
Chatterjee, Nilanjan ;
Kalaylioglu, Zeynep ;
Moslehi, Roxana ;
Peters, Ulrike ;
Wacholder, Sholom .
AMERICAN JOURNAL OF HUMAN GENETICS, 2006, 79 (06) :1002-1016
[6]   Comparing the power of linkage detection by the transmission disequilibrium test and the identity-by-descent test [J].
ClergetDarpoux, F ;
Babron, MC ;
Bickeboller, H .
GENETIC EPIDEMIOLOGY, 1995, 12 (06) :583-588
[7]   A NEW METHOD TO TEST GENETIC MODELS IN HLA ASSOCIATED DISEASES - THE MASC METHOD [J].
CLERGETDARPOUX, F ;
BABRON, MC ;
PRUM, B ;
LATHROP, GM ;
DESCHAMPS, I ;
HORS, J .
ANNALS OF HUMAN GENETICS, 1988, 52 :247-258
[8]   Population genetics models of common diseases [J].
Di Rienzo, Anna .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 2006, 16 (06) :630-636
[9]  
DIZIER MH, 1994, AM J HUM GENET, V55, P1042
[10]   Maternal genetic effects, exerted by genes involved in homocysteine remethylation, influence the risk of spina bifida [J].
Doolin, MT ;
Barbaux, S ;
McDonnell, M ;
Hoess, K ;
Whitehead, AS ;
Mitchell, LE .
AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 71 (05) :1222-1226