Conjugate Michael additions with mixed diorganozincs

被引：62

作者：

Jones, P ^{[1
]}

Reddy, CK ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] Univ Marburg, Fachbereich Chem, D-35032 Marburg, Germany

来源：

TETRAHEDRON | 1998年 / 54卷 / 08期

关键词：

D O I：

10.1016/S0040-4020(97)10382-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Functionalised mixed alkyl(trimethylsilylmethyl)zinc reagents add efficiently to a wide variety of Michael accepters in high yield and with exclusive 1,4-regioselectivity, without the need for transition metal catalysis. The trimethylsilylmethyl group behaves as a nontransferable group, and in no cases was transfer of this group observed. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1471 / 1490

页数：20

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