An expeditious route to eight- and nine-membered carbocycles based on a RCM-ring fragmentation strategy

被引：21

作者：

Rodríguez, JR

Castedo, L

Mascareñas, JL ^{[1
]}

机构：

[1] Univ Santiago de Compostela, CSIC, Dept Quim Organ, Santiago De Compostela 15706, Spain

[2] Univ Santiago de Compostela, CSIC, Unidad Asociada, Santiago De Compostela 15706, Spain

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 20期

关键词：

D O I：

10.1021/ol0063959

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The presence of a temporary one-atom internal tether in 1,9-deca- and 1,10-undecadienes allows their efficient ring closing metathesis (RCM). Cleavage of the bridging tether of the resulting bicycles provides eight- or nine-membered carbocycles, medium-sized rings that are difficult to assemble using other currently available procedures.

引用

页码：3209 / 3212

页数：4

共 36 条

[1]

Armstrong SK, 1998, J CHEM SOC PERK T 1, P371

[2] An expeditious construction of 9-membered rings [J].