Effects of expectancies on subjective responses to oral Δ9-tetrahydrocannabinol

被引:73
作者
Kirk, JM
Doty, P
de Wit, H
机构
[1] Univ Chicago, Dept Psychiat MC3077, Chicago, IL 60637 USA
[2] Cato Res Ltd, Durham, NC 27713 USA
关键词
Delta(9)-THC; cannabinoids; expectancies; marijuana users; subjective drug effects;
D O I
10.1016/S0091-3057(97)00414-0
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The effects of expectancies on subjective responses to oral Delta(9)-tetrahydrocannabinol (Delta(9)-THC) were examined. Thirty-five regular marijuana users were assigned to one of two groups: one group was told that they may receive a cannabinoid or placebo and a second group was told that they may receive a drug from one of several classes of drugs (e.g., stimulant, sedative, antiemetic) or placebo. Regardless of the group to which they were assigned, subjects received each of two oral doses of Delta(9)-THC (7.5 and 15 mg) and placebo, one dose per session, for a total of three sessions. Measures of subjective effects, including visual analog scales and the Addiction Research Center Inventory (ARCI), were administered at 0.5-h intervals throughout each session. Consistent with previous research using other drugs, subjects in the current experiment who expected to receive a cannabinoid reported greater pleasurable effects than subjects who did not have this expectancy. The used in both recreational and clinical settings. results have implications for understanding the effects of cannabinoids when (C) 1998 Elsevier Science Inc.
引用
收藏
页码:287 / 293
页数:7
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