Inhaled beclometasone dipropionate/formoterol fumarate extrafine fixed combination for the treatment of asthma

被引：11

作者：

Crisafulli, Ernesto ^{[1
]}

Zanini, Andrea ^{[2
]}

Pisi, Giovanna ^{[3
]}

Pignatti, Patrizia ^{[4
]}

Poli, Gianluigi ^{[5
]}

Scuri, Mario ^{[5
]}

Chetta, Alfredo ^{[1
]}

机构：

[1] Univ Parma, Dept Clin & Expt Med, Resp Dis & Lung Funct Unit, Via Gramsci 14, I-43126 Parma, Italy

[2] Malcantonese Hosp, Giuseppe Rossi Fdn, Div Internal & Resp Med, Castelrotto, Switzerland

[3] Univ Hosp, Dept Paediat, Cyst Fibrosis Unit, Parma, Italy

[4] Salvatore Maugeri Fdn IRCCS, Allergy & Immunol Unit, Pavia, Italy

[5] Chiesi Farmaceut SpA, Parma, Italy

来源：

EXPERT REVIEW OF RESPIRATORY MEDICINE | 2016年 / 10卷 / 05期

关键词：

Asthma; small airways; inflammation; beclometasone dipropionate; formoterol fumarate; extrafine; fixed combination; pMDI; DPI; LONG-ACTING BETA(2)-AGONISTS; AIRWAY SMOOTH-MUSCLE; SINGLE INHALER; REAL-LIFE; BECLOMETHASONE DIPROPIONATE/FORMOTEROL; FLUTICASONE PROPIONATE; SCIENTIFIC RATIONALE; PATIENT PERSPECTIVES; ADULT PATIENTS; LUNG-FUNCTION;

D O I：

10.1586/17476348.2016.1161508

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

100201 [内科学];

摘要：

Inhaled therapy is often considered the cornerstone of asthma management and international guidelines recommend combination therapy of inhaled corticosteroids (ICS) and long-acting-beta2-agonists (LABA) in a large proportion of asthmatic patients. The effectiveness of ICS/LABA is dependent on the correct choice of device and proper inhalation technique, this influences drug delivery and distribution along the bronchial tree, including the most peripheral airways. The fixed combination of beclometasone dipropionate/formoterol fumarate (BDP/FF) is the only extrafine formulation available in pressurized metered dose inhaler (pMDI) and in dry powder inhaler (DPI). Here, we focus on the recent significant advances regarding BDP/FF fixed combination for the treatment of asthma.

引用

页码：481 / 490

页数：10

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