Angiogenesis and organ transplantation

被引：13

作者：

Rajnoch, J ^{[1
]}

Viklicky, O ^{[1
]}

机构：

[1] Transplant Ctr, Inst Clin & Expt Med, Dept Nephrol, Prague 14021, Czech Republic

来源：

FOLIA MICROBIOLOGICA | 2004年 / 49卷 / 05期

关键词：

D O I：

10.1007/BF02931524

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

Angiogenesis is a vessel development process that maintains the vascular supply for organ function. Regulation of angiogenesis is provided by positive factors, such as vascular endothelial or basic fibroblast growth factors, and negative factors, such as thrombospondin and macrophage-derived inflammatory cytokines. While the role of angiogenesis in the wound healing, embryogenesis, tumor growth and proliferative diseases is clear, in organ transplantation it is not yet well established. Herein we discuss the potential role of angiogenesis in chronic renal disease and in transplant settings.

引用

页码：499 / 505

页数：7

共 45 条

[1]

Renal ischemia-reperfusion injury:: an inescapable event affecting kidney transplantation outcome [J].

Böhmová, R ;

Viklicky, O .

FOLIA MICROBIOLOGICA, 2001, 46 (04) :267-276

[2]

TGF-β signaling in renal disease [J].

Böttinger, EP ;

Bitzer, M .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2002, 13 (10) :2600-2610

[3]

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele [J].

Carmeliet, P ;

Ferreira, V ;

Breier, G ;

Pollefeyt, S ;

Kieckens, L ;

Gertsenstein, M ;

Fahrig, M ;

Vandenhoeck, A ;

Harpal, K ;

Eberhardt, C ;

Declercq, C ;

Pawling, J ;

Moons, L ;

Collen, D ;

Risau, W ;

Nagy, A .

NATURE, 1996, 380 (6573) :435-439

[4]

Cines DB, 1998, BLOOD, V91, P3527

[5]

Thrombospondins and tumor angiogenesis [J].

de Fraipont, F ;

Nicholson, AC ;

Feige, JJ ;

Van Meir, EG .

TRENDS IN MOLECULAR MEDICINE, 2001, 7 (09) :401-407

[6]

DVORAK HF, 1987, LAB INVEST, V57, P673

[7]

Plasticity of kidney cells: Role in kidney remodeling and scarring [J].

El Nahas, AM .

KIDNEY INTERNATIONAL, 2003, 64 (05) :1553-1563

[8]

Etoh T, 2000, CLIN CANCER RES, V6, P3545

[9]

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene [J].

Ferrara, N ;

CarverMoore, K ;

Chen, H ;

Dowd, M ;

Lu, L ;

OShea, KS ;

PowellBraxton, L ;

Hillan, KJ ;

Moore, MW .

NATURE, 1996, 380 (6573) :439-442

[10]

Molecular and biological properties of vascular endothelial growth factor [J].

Ferrara, N .

JOURNAL OF MOLECULAR MEDICINE-JMM, 1999, 77 (07) :527-543

← 1 2 3 4 5 →