Microcrimped Collagen Fiber-Elastin Composites

被引：48

作者：

Caves, Jeffrey M. ^{[1
,2
]}

Kumar, Vivek A. ^{[1
,2
]}

Xu, Wenjun ^{[3
,4
]}

Naik, Nisarga ^{[3
,4
]}

Allen, Mark G. ^{[3
,4
]}

Chaikof, Elliot L. ^{[1
,2
]}

机构：

[1] Emory Univ, Dept Biomed Engn, Georgia Inst Technol, Atlanta, GA 30322 USA

[2] Emory Univ, Dept Surg, Georgia Inst Technol, Atlanta, GA 30322 USA

[3] Georgia Inst Technol, Sch Elect Engn, Atlanta, GA 30332 USA

[4] Georgia Inst Technol, Sch Comp Engn, Atlanta, GA 30332 USA

来源：

ADVANCED MATERIALS | 2010年 / 22卷 / 18期

关键词：

MECHANICAL-PROPERTIES; BIOMECHANICAL PROPERTIES; TISSUE; WALL; ELECTRONICS; POLYMERS; SILICON; TENDON; GRAFT; RAT;

D O I：

10.1002/adma.200903612

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

A flexible membrane templating technique (a) is developed for the fabrication of microcrimped collagen microfibers (b) that are embedded in an elastin-like protein matrix to generate hierarchical, biologically inspired fiber-reinforced composites (c). The microcrimped structure is stable under cyclic loading and the mechanical response of the engineered collagen-elastin composite mimics that of native tissue.

引用

页码：2041 / +

页数：5

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