Hepatitis B virus genotype C takes a more aggressive disease course than hepatitis B virus genotype B in hepatitis B e antigen-positive patients

被引:120
作者
Chan, HLY [1 ]
Wong, ML [1 ]
Hui, AY [1 ]
Hung, LCT [1 ]
Chan, FKL [1 ]
Sung, JJY [1 ]
机构
[1] Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China
关键词
D O I
10.1128/JCM.41.3.1277-1279.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
One hundred forty-six hepatitis B e antigen (HBeAg) -positive chronic hepatitis B patients were followed up for 32 +/- 13 months. All six patients with hepatocellular carcinoma had hepatitis B virus (HBV) genotype C. Disease activity was greater in patients infected by HBV genotype C than in those infected by HBV genotype B in the HBeAg-positive phase but not after HBeAg seroconversion.
引用
收藏
页码:1277 / 1279
页数:3
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