A general, [1+4] approach to the synthesis of 3(5)-substituted pyrazoles from aldehydes.

被引：37

作者：

Almirante, N ^{[1
]}

Cerri, A ^{[1
]}

Fedrizzi, G ^{[1
]}

Marazzi, G ^{[1
]}

Santagostino, M ^{[1
]}

机构：

[1] Prassis Ist Ric Sigma Tau, I-20019 Settimo Milanese, MI, Italy

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 20期

关键词：

D O I：

10.1016/S0040-4039(98)00472-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new, one-pot preparation of 3(5)-substituted-1H-pyrazole is described that employs Homer-Emmons reaction of aldehydes with dianion of novel phosphonate 1 and proceeds through cyclization of N-sodium salt of alpha,beta-unsaturated tosylhydrazones 2. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3287 / 3290

页数：4

共 22 条

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