Apoptosis: A new pharmacodynamic endpoint

被引：37

作者：

Au, JLS

Panchal, N

Li, D

Gan, YB

机构：

[1] Ohio State Univ, Coll Pharm, Columbus, OH 43210 USA

[2] Ohio State Univ, Ctr Comprehens Canc, Columbus, OH 43210 USA

来源：

PHARMACEUTICAL RESEARCH | 1997年 / 14卷 / 12期

关键词：

apoptosis; programmed cell death; drug induced apoptosis; pharmacodynamic endpoint;

D O I：

10.1023/A:1012159208559

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：1659 / 1671

页数：13

共 197 条

[71]

Haldar S, 1996, CANCER RES, V56, P1253

[72]

Haldar S, 1997, CANCER RES, V57, P229

[73] Apoptosis: Molecular regulation of cell death [J].

Hale, AJ ;

Smith, CA ;

Sutherland, LC ;

Stoneman, VEA ;

Longthorne, VL ;

Culhane, AC ;

Williams, GT .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1996, 236 (01) :1-26

[74] The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein [J].

Han, JH ;

Sabbatini, P ;

Perez, D ;

Rao, L ;

Modha, D ;

White, E .

GENES & DEVELOPMENT, 1996, 10 (04) :461-477

[75] Functions of ceramide in coordinating cellular responses to stress [J].

Hannun, YA .

SCIENCE, 1996, 274 (5294) :1855-1859

[76]

HARPER JW, 1993, CELL, V75, P805

[77] INDUCTION OF APOPTOSIS IN HELA-CELLS BY TRANS-ACTIVATION-DEFICIENT P53 [J].

HAUPT, Y ;

ROWAN, S ;

SHAULIAN, E ;

VOUSDEN, KH ;

OREN, M .

GENES & DEVELOPMENT, 1995, 9 (17) :2170-2183

[78] MEDIATION OF C-MYC-INDUCED APOPTOSIS BY P53 [J].

HERMEKING, H ;

EICK, D .

SCIENCE, 1994, 265 (5181) :2091-2093

[79] Apoptosis and chemotherapy resistance [J].

Hickman, JA .

EUROPEAN JOURNAL OF CANCER, 1996, 32A (06) :921-926

[80] BCL-2 IS AN INNER MITOCHONDRIAL-MEMBRANE PROTEIN THAT BLOCKS PROGRAMMED CELL-DEATH [J].

HOCKENBERY, D ;

NUNEZ, G ;

MILLIMAN, C ;

SCHREIBER, RD ;

KORSMEYER, SJ .

NATURE, 1990, 348 (6299) :334-336

← 3 4 5 6 7 8 9 10 11 12 →