Drug addiction - Cocaine and the serotonin saga

被引：23

作者：

White, FJ ^{[1
]}

机构：

[1] Finch Univ Hlth Sci Chicago Med Sch, Dept Mol & Cellular Pharmacol, N Chicago, IL 60064 USA

来源：

NATURE | 1998年 / 393卷 / 6681期

关键词：

D O I：

10.1038/30105

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

To devise ways to treat cocaine addiction, the cellular mechanisms behind that addiction have to be understood. One study goes some way to doing this by generating mice that lack the serotonin-1B receptor. Before this study, nobody could say for sure whether the neurotransmitter serotonin was involved in the processes that underlie vulnerability to cocaine addiction. But the responses of the knockout mice to cocaine now indicate that it is — through this receptor at least.

引用

页码：118 / 119

页数：2

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