Skeletal muscle anabolism in patients with advanced cancer

被引:45
作者
Baracos, Vickie E. [1 ]
机构
[1] Univ Alberta, Dept Oncol, Edmonton, AB T6G 1Z2, Canada
关键词
CACHEXIA; THERAPY;
D O I
10.1016/S1470-2045(14)71185-4
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
引用
收藏
页码:13 / 14
页数:3
相关论文
共 10 条
[1]
Effects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial [J].
Dobs, Adrian S. ;
Boccia, Ralph V. ;
Croot, Christopher C. ;
Gabrail, Nashat Y. ;
Dalton, James T. ;
Hancock, Michael L. ;
Johnston, Mary A. ;
Steiner, Mitchell S. .
LANCET ONCOLOGY, 2013, 14 (04) :335-345
[2]
Garcia JM, 2014, LANCET ONCOL
[3]
Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia [J].
Kir, Serkan ;
White, James P. ;
Kleiner, Sandra ;
Kazak, Lawrence ;
Cohen, Paul ;
Baracos, Vickie E. ;
Spiegelman, Bruce M. .
NATURE, 2014, 513 (7516) :100-+
[4]
Effect of 10 days of bed rest on skeletal muscle in healthy older adults [J].
Kortebein, Patrick ;
Ferrando, Arny ;
Lombeida, Juan ;
Wolfe, Robert ;
Evans, William J. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 297 (16) :1772-1774
[5]
Habitual Myofibrillar Protein Synthesis Is Normal in Patients with Upper GI Cancer Cachexia [J].
MacDonald, Alisdair J. ;
Johns, Neil ;
Stephens, Nathan ;
Greig, Carolyn ;
Ross, James A. ;
Small, Alexandra C. ;
Husi, Holger ;
Fearon, Kenneth C. H. ;
Preston, Tom .
CLINICAL CANCER RESEARCH, 2015, 21 (07) :1734-1740
[6]
Skeletal muscle anabolism is a side effect of therapy with the MEK inhibitor: selumetinib in patients with cholangiocarcinoma [J].
Prado, C. M. M. ;
Bekaii-Saab, T. ;
Doyle, L. A. ;
Shrestha, S. ;
Ghosh, S. ;
Baracos, V. E. ;
Sawyer, M. B. .
BRITISH JOURNAL OF CANCER, 2012, 106 (10) :1583-1586
[7]
Central tenet of cancer cachexia therapy: do patients with advanced cancer have exploitable anabolic potential? [J].
Prado, Carla M. ;
Sawyer, Michael B. ;
Ghosh, Sunita ;
Lieffers, Jessica R. ;
Esfandiari, Nina ;
Antoun, Sami ;
Baracos, Vickie E. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2013, 98 (04) :1012-1019
[8]
Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study [J].
Prado, Carla M. M. ;
Liefers, Jessica R. ;
McCargar, Linda J. ;
Reiman, Tony ;
Sawyer, Michael B. ;
Martin, Lisa ;
Baracos, Vickie E. .
LANCET ONCOLOGY, 2008, 9 (07) :629-635
[9]
Normal protein anabolic response to hyperaminoacidemia in insulin-resistant patients with lung cancer cachexia [J].
Winter, Aaron ;
MacAdams, Jacqueline ;
Chevalier, Stephanie .
CLINICAL NUTRITION, 2012, 31 (05) :765-773
[10]
Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival [J].
Zhou, Xiaolan ;
Wang, Jin Lin ;
Lu, John ;
Song, Yanping ;
Kwak, Keith S. ;
Jiao, Qingsheng ;
Rosenfeld, Robert ;
Chen, Qing ;
Boone, Thomas ;
Simonet, W. Scott ;
Lacey, David L. ;
Goldberg, Alfred L. ;
Han, H. Q. .
CELL, 2010, 142 (04) :531-543