Putting the brake on drive:: meiotic drive of t haplotypes in natural populations of mice

被引：51

作者：

Ardlie, KG ^{[1
]}

机构：

[1] Harvard Univ, Museum Comparat Zool, Cambridge, MA 02138 USA

来源：

TRENDS IN GENETICS | 1998年 / 14卷 / 05期

关键词：

D O I：

10.1016/S0168-9525(98)01455-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Mouse t haplotypes are a 'selfish' form of chromosome 17 that show non-mendelian transmission from heterozygous +/t males. The considerable transmission bias in favour of t haplotypes should result in very high frequencies of these chromosomes in natural populations, but they seldom occur at the high frequencies expected. Recent research on this and other meiotic drive systems has shown bow a variety of mechanisms have evolved to suppress drive, and to re-establish mendelian segregation.

引用

页码：189 / 193

页数：5

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