Controversies in urinary iodine determinations

被引:90
作者
Soldin, OP [1 ]
机构
[1] Soldin Res & Consultants Inc, Bethesda, MD USA
[2] Hosp Sick Children, Div Clin Pharmacol, Motherisk, Toronto, ON M5G 1X8, Canada
关键词
urinary iodide measurement; iodine deficiency; environmental; thyroid diseases; epidemiology; thyroid hormones; pregnancy; review;
D O I
10.1016/S0009-9120(02)00406-X
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Iodine deficiency (ID) is associated with increased prevalence of goiter, increased risk for neurodevelopmental disorders, and is the world's leading cause of intellectual deficits. Iodine nutritional status of a population is assessed by measurements of urinary iodine concentrations which are also used to define, indicate, survey and monitor iodine deficiency and consequently its treatment. Several methods are available for urinary iodine determination. Discussed here are some of the limitations,and controversies related to urinary iodine determinations, and recent findings with emphasis on measurements of-urinary iodine concentrations in children and during pregnancy. (C) 2002 The Canadian Society of Clinical Chemists. All rights reserved.
引用
收藏
页码:575 / 579
页数:5
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