PhenomicDB: a multi-species genotype/phenotype database for comparative phenomics

被引：45

作者：

Kahraman, A

Avramov, A

Nashev, LG

Popov, D

Ternes, R

Pohlenz, HD

Weiss, B ^{[1
]}

机构：

[1] Schering AG, Res Labs, D-13342 Berlin, Germany

[2] Univ Appl Sci Giessen, Dept Bioinformat, D-35596 Giessen, Germany

[3] Metalife AG, D-79297 Winden, Germany

来源：

BIOINFORMATICS | 2005年 / 21卷 / 03期

关键词：

D O I：

10.1093/bioinformatics/bti010

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We have created PhenomicDB, a multi-species genotype/phenotype database by merging public genotype/phenotype data from a wide range of model organisms and Homo sapiens. Until now these data were available in distinct organism-specific databases (e.g. WormBase, OMIM, FlyBase and MGI). We compiled this wealth of data into a single integrated resource by coarse-grained semantic mapping of the phenotypic data fields, by including common gene indices (NCBI Gene), and by the use of associated orthology relationships. With its use-case-oriented user interface, PhenomicDB allows scientists to compare and browse known phenotypes for a given gene or a set of genes from different organisms simultaneously.

引用

页码：418 / 420

页数：3

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