Selectivity for the spatial and nonspatial attributes of auditory stimuli in the ventrolateral prefrontal cortex

被引:49
作者
Cohen, YE [1 ]
Russ, BE
Gifford, GW
Kiringoda, R
MacLean, KA
机构
[1] Dartmouth Coll, Dept Psychol & Brain Sci, Hanover, NH 03755 USA
[2] Dartmouth Coll, Ctr Cognit Neurosci, Hanover, NH 03755 USA
关键词
spatial processing; nonspatial processing; prefrontal cortex; auditory; rhesus; vocalization;
D O I
10.1523/JNEUROSCI.3935-04.2004
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Spatial and nonspatial auditory processing is hypothesized to occur in parallel dorsal and ventral pathways, respectively. In this study, we tested the spatial and nonspatial sensitivity of auditory neurons in the ventrolateral prefrontal cortex (vPFC), a cortical area in the hypothetical nonspatial pathway. We found that vPFC neurons were modulated significantly by both the spatial and nonspatial attributes of an auditory stimulus. When comparing these responses with those in anterolateral belt region of the auditory cortex, which is hypothesized to be specialized for processing the nonspatial attributes of auditory stimuli, we found that the nonspatial sensitivity of vPFC neurons was poorer, whereas the spatial selectivity was better than anterolateral neurons. Also, the spatial and nonspatial sensitivity of vPFC neurons was comparable with that seen in the lateral intraparietal area, a cortical area that is a part of the dorsal pathway. These data suggest that substantial spatial and nonspatial processing occurs in both the dorsal and ventral pathways.
引用
收藏
页码:11307 / 11316
页数:10
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