Sequence-based cancer genomics: Progress, lessons and opportunities

被引：44

作者：

Strausberg, RL

Simpson, AJG

Wooster, R

机构：

[1] NCI, Bethesda, MD 20892 USA

[2] Ludwig Inst Canc Res, New York, NY 10158 USA

[3] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England

来源：

NATURE REVIEWS GENETICS | 2003年 / 4卷 / 06期

基金：

巴西圣保罗研究基金会;

关键词：

D O I：

10.1038/nrg1085

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Technologies that provide a genome-wide view offer an unprecedented opportunity to scrutinize the molecular biology of the cancer cell. The information that is derived from these technologies is well suited to the development of public databases of alterations in the cancer genome and its expression. Here, we describe the synergistic efforts of research programmes in Brazil, the United Kingdom and the United States towards building integrated databases that are widely accessible to the research community, to enable basic and applied applications in cancer research.

引用

页码：409 / 418

页数：10

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