Comparison of persistent organic pollutant residues in serum and adipose tissue in a female population in Belgium, 1996-1998

被引:79
作者
Pauwels, A
Covaci, A
Weyler, J
Delbeke, L
Dhont, M
De Sutter, P
D'Hooghe, T
Schepens, PJC
机构
[1] Univ Antwerp, Toxicol Ctr Pharmaceut Sci, B-2610 Wilrijk, Belgium
[2] Dept Med, B-2610 Wilrijk, Belgium
[3] Univ Antwerp Hosp, Ctr Reprod Med, B-2650 Edegem, Belgium
[4] State Univ Ghent Hosp, Ctr Infertil, B-9000 Ghent, Belgium
[5] Univ Hosp Gasthuisberg, Ctr Reprod Med, B-3000 Louvain, Belgium
关键词
D O I
10.1007/s002440010104
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
This study was performed to determine and compare persistent organic pollutant (POP) levels in different matrices in a female population. A total of 96 serum and 46 adipose tissue samples were collected from infertile women (n = 101) attending Centers for Reproductive Medicine in Belgium from 1996 to 1998. Gas chromatography with electron-capture detection was used to quantify residue levels on a lipid basis of seven organochlorine pesticides (OCPs) and seven polychlorinated biphenyls (PCBs). There was a strong association between adipose tissue and serum residues. The adipose tissue levels of CB-138, 153, 180 and p,p'-DDE were explained by the serum residues. Besides, the accumulation pattern for CB-153 and CB-180 in serum and adipose tissue are mirror images of each other.
引用
收藏
页码:265 / 270
页数:6
相关论文
共 25 条
[1]   POLYCHLORINATED-BIPHENYLS, 1,1,1-TRICHLORO-2,2-BIS(P-CHLOROPHENYL)ETHANE (P,P'-DDT) AND 1,1-DICHLORO-2,2-BIS(P-CHLOROPHENYL)-ETHYLENE (P,P'-DDE) IN HUMAN PLASMA RELATED TO FISH CONSUMPTION [J].
ASPLUND, L ;
SVENSSON, BG ;
NILSSON, A ;
ERIKSSON, U ;
JANSSON, B ;
JENSEN, S ;
WIDEQVIST, U ;
SKERFVING, S .
ARCHIVES OF ENVIRONMENTAL HEALTH, 1994, 49 (06) :477-486
[2]   An improved analysis for chlorinated pesticides and polychlorinated biphenyls (PCBs) in human and bovine sera using solid-phase extraction [J].
Brock, JW ;
Burse, VW ;
Ashley, DL ;
Najam, AR ;
Green, VE ;
Korver, MP ;
Powell, MK ;
Hodge, CC ;
Needham, LL .
JOURNAL OF ANALYTICAL TOXICOLOGY, 1996, 20 (07) :528-536
[3]  
BROUWER A, 1995, EUR J PHARM-ENVIRON, V293, P1
[4]   THE WILDLIFE HUMAN CONNECTION - MODERNIZING RISK-DECISIONS [J].
COLBORN, T .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1994, 102 :55-59
[5]   ORGANOCHLORINE PESTICIDES AND PCBS IN TISSUES FROM DUTCH CITIZENS (1968-1986) [J].
GREVE, PA ;
VANZOONEN, P .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 1990, 38 (02) :265-277
[6]   Monitoring of polychlorinated biphenyls in human blood plasma: Methodological developments and influence of age, lactation, and fish consumption [J].
Grimvall, E ;
Rylander, L ;
NilssonEhle, P ;
Nilsson, U ;
Stromberg, U ;
Hagmar, L ;
Ostman, C .
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1997, 32 (03) :329-336
[7]   A COMPARISON OF ORGANOCHLORINE PESTICIDE-RESIDUES IN MATERNAL ADIPOSE-TISSUE, MATERNAL BLOOD, CORD BLOOD, AND HUMAN-MILK FROM MOTHER INFANT PAIRS [J].
KANJA, LW ;
SKAARE, JU ;
OJWANG, SBO ;
MAITAI, CK .
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1992, 22 (01) :21-24
[8]   Congener-specific distribution of polychlorinated biphenyls in brain regions, blood, liver, and fat of adult rats following repeated exposure to Aroclor 1254 [J].
Kodavanti, PRS ;
Ward, TR ;
Derr-Yellin, EC ;
Mundy, WR ;
Casey, AC ;
Bush, B ;
Tilson, HA .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1998, 153 (02) :199-210
[9]   AUTOMATED BLOOD-PRESSURE RECORDING - THE PHENOMENON OF BLOOD-PRESSURE ELEVATIONS DURING SPEECH [J].
MALINOW, KL ;
LYNCH, JJ ;
THOMAS, SA ;
FRIEDMANN, E ;
LONG, JM .
ANGIOLOGY, 1982, 33 (07) :474-479
[10]   The CALUX (chemical-activated luciferase expression) assay adapted and validated for measuring TCDD equivalents in blood plasma [J].
Murk, AJ ;
Leonards, PEG ;
Bulder, AS ;
Jonas, AS ;
Rozemeijer, MJC ;
Denison, MS ;
Koeman, JH ;
Brouwer, A .
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 1997, 16 (08) :1583-1589