Controlled release from crosslinked degradable networks

被引：77

作者：

Davis, KA

Anseth, KS

机构：

[1] Univ Colorado, Dept Chem Engn, Boulder, CO 80309 USA

[2] Univ Colorado, Howard Hughes Med Inst, Boulder, CO 80309 USA

来源：

CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS | 2002年 / 19卷 / 4-5期

关键词：

hydrophobic networks; PEG hydrogels; drug delivery;

D O I：

10.1615/CritRevTherDrugCarrierSyst.v19.i45.30

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This article reviews controlled release from crosslinked degradable networks. Network formulations include those derived from wholly synthetic components, natural components, and combinations thereof. This includes, but is not limited to, poly(orthoesters), poly(anhydrides), poly(ethylene glycol) (PEG) derivatives, and dextran functional macromonomers. In addition, we present a discussion of the chemistry behind novel degradable networks with potential use in the controlled release realm.

引用

页码：385 / 423

页数：39

共 140 条

[1] Photoscissable hydrogel synthesis via rapid photopolymerization of novel PEG-based polymers in the absence of photoinitiators [J].