The potential role of podoplanin in tumour invasion

被引：243

作者：

Wicki, A. ^{[1
]}

Christofori, G. ^{[1
]}

机构：

[1] Univ Basel, Dept Clin Biol Sci, Inst Biochem & Genet, Ctr Biomed, CH-4058 Basel, Switzerland

来源：

BRITISH JOURNAL OF CANCER | 2007年 / 96卷 / 01期

关键词：

cadherin; cancer; cytoskeleton; EMT; invasion; podoplanin;

D O I：

10.1038/sj.bjc.6603518

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Podoplanin is a small mucin-like transmembrane protein, widely expressed in various specialised cell types throughout the body. Here, we revisit the mechanism of podoplanin-mediated tumour invasion. We compare molecular pathways leading to single and collective cell invasion and discuss novel distinct concepts of tumour cell invasion.

引用

页码：1 / 5

页数：5

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