One-pot amide synthesis from allyl or benzyl halides and amines by Pd-catalysed carbonylation

被引：47

作者：

Troisi, Luigino ^{[1
]}

Granito, Catia ^{[1
]}

Rosato, Francesca ^{[1
]}

Videtta, Valeria ^{[1
]}

机构：

[1] Univ Lecce, Dipartimento Sci & Tecnol Biol & Ambientali, I-73100 Lecce, Italy

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 02期

关键词：

Amides; Halides; Amines; Palladium-catalysed carbonylation; STEREOSELECTIVE-SYNTHESIS; 2+2 CYCLOADDITION; ORGANIC HALIDES; CARBON-MONOXIDE; ALKYL IODIDES; PALLADIUM; ISOMERIZATION; ARYL;

D O I：

10.1016/j.tetlet.2009.11.023

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Amides can be prepared from allyl or benzyl halides and primary or secondary amines, using Pd(O) catalyst under CO pressure, in a one-pot synthesis. The reaction proceeds through the acyl palladium halide formation which undergoes an acylic nucleophilic substitution from the amine. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：371 / 373

页数：3

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