Accelerated rejection following offspring-to-mother and husband-to-wife transplants

被引：22

作者：

Rosenberg, JC

Jones, B

Oh, H

机构：

[1] Transplantat Soc Michigan, Gift Life Michigan, Histocompatibil Lab, Ann Arbor, MI 48104 USA

[2] St John Hosp Transplant Ctr, Detroit, MI USA

来源：

CLINICAL TRANSPLANTATION | 2004年 / 18卷 / 06期

关键词：

accelerated rejection; anamnestic reaction; offspring-to-mother transplant; husband-to-wife transplant; immunologic mechanisms of rejection;

D O I：

10.1111/j.1399-0012.2004.00250.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

It has been demonstrated that graft survival rates of offspring-to-mother and husband-to-wife renal transplants are equivalent to those of other living donors. Although the vast majority of these transplants proceed without incident, we have encountered several instances of delayed accelerated rejections that are not predicted by a positive cross-match. The accelerated rejection can result from an anamnestic reaction subsequent to the in utero exposure of the mother to human leukocyte antigen (HLA) antigens of the fetus with sensitization developing during the pregnancy.

引用

页码：729 / 733

页数：5

共 16 条

[1]

Advisory Committee to the Renal Transplant Registry, 1972, JAMA-J AM MED ASSOC, V221, P1495

[2]

BERKE J, 1974, J OBSTET GYNEACOL BR, V81, P222

[3] Role of humoral immune reactions as target for antirejection therapy in recipients of a spousal-donor kidney graft [J].