Liver enzyme alteration: a guide for clinicians

被引：1290

作者：

Giannini, EG ^{[1
]}

Testa, R ^{[1
]}

Savarino, V ^{[1
]}

机构：

[1] Univ Genoa, Dept Internal Med, Gastroenterol Unit, I-16132 Genoa, Italy

来源：

CANADIAN MEDICAL ASSOCIATION JOURNAL | 2005年 / 172卷 / 03期

关键词：

D O I：

10.1503/cmaj.1040752

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

ISOLATED ALTERATIONS OF BIOCHEMICAL MARKERS OF LIVER DAMAGE in a seemingly healthy patient can present a challenge for the clinician. In this review we provide a guide to interpreting alterations to liver enzyme levels. The functional anatomy of the liver and pathophysiology of liver enzyme alteration are briefly reviewed. Using a schematic approach that classifies enzyme alterations as predominantly hepatocellular or predominantly cholestatic, we review abnormal enzymatic activity within the 2 subgroups, the most common causes of enzyme alteration and suggested initial investigations.

引用

页码：367 / 379

页数：13

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