The role of histology in idiopathic pulmonary fibrosis: An update

被引：25

作者：

Cavazza, Alberto ^{[1
]}

Rossi, Giulio ^{[2
]}

Carbonelli, Cristiano ^{[3
]}

Spaggiari, Lucia ^{[4
]}

Paci, Massimiliano ^{[5
]}

Roggeri, Alberto ^{[3
]}

机构：

[1] Osped Santa Maria Nuova, Unita Operat Anat Patol, I-42100 Reggio Emilia, Italy

[2] Azienda Policlin, Unit Pathol, Modena, Italy

[3] Azienda Osped Santa Maria Nuova, Unit Pulmunol, Reggio Emilia, Italy

[4] Azienda Osped Santa Maria Nuova, Radiol Unit, Reggio Emilia, Italy

[5] Azienda Osped Santa Maria Nuova, Unit Thorac Surg, Reggio Emilia, Italy

来源：

RESPIRATORY MEDICINE | 2010年 / 104卷

关键词：

Idiopathic pulmonary fibrosis; Usual interstitial pneumonia; Non-specific interstitial pneumonia; Diffuse parenchymal lung disease; Histology; Review; INTERSTITIAL LUNG-DISEASE; ACUTE EXACERBATION; INTEROBSERVER VARIATION; RESPIRATORY BRONCHIOLITIS; CONSENSUS CLASSIFICATION; PROGNOSTIC IMPLICATIONS; TRANSBRONCHIAL BIOPSY; COMPUTED-TOMOGRAPHY; CLINICAL-COURSE; PNEUMONIA;

D O I：

10.1016/j.rmed.2010.03.013

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

The diagnosis of idiopathic pulmonary fibrosis (IPF) currently requires an integrated clinical radiological pathological approach in which the histology plays a different role from in the past. The first reason for this change is that non-invasive diagnostic procedures, particularly pulmonary function tests and high resolution computed tomography, have become increasingly competitive with biopsy in providing prognostic information. The other reason is a better appreciation of the limitations of histology: sampling error and interobserver variation. In this review we analyze the reasons for this change of perspective, provide an update on the practical role of histology in the diagnosis of IPF and discuss some of its complications. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：S11 / S22

页数：12

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