Determination of epinephrine based on its enhancement for electrochemiluminescence of lucigenin

被引：79

作者：

Su, YY ^{[1
]}

Wang, JA ^{[1
]}

Chen, GN ^{[1
]}

机构：

[1] Fuzhou Univ, Dept Chem, Fuzhou 350002, Peoples R China

来源：

TALANTA | 2005年 / 65卷 / 02期

关键词：

electrochemiluminescence; epinephrine; lucigenin; anodic potential sweep;

D O I：

10.1016/j.talanta.2004.07.015

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Epinephrine was found to be able to strongly enhance the electrochemiluminescence (ECL) of lucigenin system by using the anodic potential sweep. Based on which. a novel ECL method for the determination of epinephrine was developed. Under the optimum condition, the enhanced ECL intensity was linear with the epinephrine concentration in the range of 4.0 x 10(-8) to 2.0 x 10(-7) mol L-1. The detection limit (defined as S/N = 3) was 2.4 x 10(-8) mol L-1, and the relative standard deviation was 2.7% for 1.0 x 10(-7) mol L-1 epinephrine (n = 11). The method was successfully applied to the determination of epinephrine in pharmaceutical samples with satisfactory results. In addition, the possible mechanism for the lucigenin ECL system in the presence of epinephrine has also been discussed. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：531 / 536

页数：6

共 33 条

[1] Electrochemical oxidation of trans-3,4-dihydroxycinnamic acid at PbO2 electrodes:: direct electrolysis and ozone mediated reactions compared [J].