Transcription of chromatin: these are complex times

被引：71

作者：

Armstrong, JA ^{[1
]}

Emerson, BM ^{[1
]}

机构：

[1] Salk Inst Biol Studies, Regulatory Biol Lab, La Jolla, CA 92037 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1998年 / 8卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0959-437X(98)80137-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Transcription of chromatin-packaged genes involves highly regulated changes in nucleosomal structure that control DNA accessibility. Two systems that facilitate these changes are ATP-dependent chromatin remodeling complexes and enzymatic complexes which control histone acetylation and deacetylation. Recent studies provide insight on the role of these remodeling machines and specific transcription factors in the expression of viral, inducible, and tissue-restricted genes. (C) Current Biology Ltd ISSN 0959-437X.

引用

页码：165 / 172

页数：8

共 59 条

[1] Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression [J].

Alland, L ;

Muhle, R ;

Hou, H ;

Potes, J ;

Chin, L ;

SchreiberAgus, N ;

DePinho, RA .

NATURE, 1997, 387 (6628) :49-55

[2] ACETYLATION + METHYLATION OF HISTONES + THEIR POSSIBLE ROLE IN REGULATION OF RNA SYNTHESIS [J].

ALLFREY, VG ;

FAULKNER, R ;

MIRSKY, AE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1964, 51 (05) :786-+

[3]

Armstrong JA, 1996, MOL CELL BIOL, V16, P5634

[4] An HMG I/Y-containing repressor complex and supercoiled DNA topology are critical for long-range enhancer-dependent transcription in vitro [J].

Bagga, R ;

Emerson, BM .

GENES & DEVELOPMENT, 1997, 11 (05) :629-639

[5] The CBP co-activator is a histone acetyltransferase [J].

Bannister, AJ ;

Kouzarides, T .

NATURE, 1996, 384 (6610) :641-643

[6] Distal enhancer regulation by promoter derepression in topologically constrained DNA in vitro [J].

Barton, MC ;

Madani, N ;

Emerson, BM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (14) :7257-7262

[7] Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation [J].

Brownell, JE ;

Zhou, JX ;

Ranalli, T ;

Kobayashi, R ;

Edmondson, DG ;

Roth, SY ;

Allis, CD .

CELL, 1996, 84 (06) :843-851

[8] Special HATs for special occasions: Linking histone acetylation to chromatin assembly and gene activation [J].

Brownell, JE ;

Allis, CD .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1996, 6 (02) :176-184

[9] The yeast SWI-SNF complex facilitates binding of a transcriptional activator to nucleosomal sites in vivo [J].

Burns, LG ;

Peterson, CL .

MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (08) :4811-4819

[10] RSC, an essential, abundant chromatin-remodeling complex [J].

Cairns, BR ;

Lorch, Y ;

Li, Y ;

Zhang, MC ;

Lacomis, L ;

ErdjumentBromage, H ;

Tempst, P ;

Du, J ;

Laurent, B ;

Kornberg, RD .

CELL, 1996, 87 (07) :1249-1260

← 1 2 3 4 5 6 →