Outcome of pregnancy in women with congenital heart disease - A literature review

被引:380
作者
Drenthen, Willem
Pieper, Petronella G.
Roos-Hesselink, Jolien W.
van Lottum, Willem A.
Voors, Adriaan A.
Mulder, Barbara J. M.
van Dijk, Arie P. J.
Vliegen, Hubert W.
Yap, Sing C.
Moons, Philip
Ebels, Tjark
van Veldhuisen, Dirk J.
机构
[1] Univ Groningen, Med Ctr, Dept Cardiol, NL-9700 RB Groningen, Netherlands
[2] Univ Groningen, Med Ctr, Dept Thorac Surg, NL-9700 RB Groningen, Netherlands
[3] Erasmus MC, Dept Cardiol, Rotterdam, Netherlands
[4] Acad Med Ctr, Dept Cardiol, Amsterdam, Netherlands
[5] Radboud Univ Nijmegen, Med Ctr, Dept Cardiol, Nijmegen, Netherlands
[6] Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands
[7] Univ Hosp Leuven, Louvain, Belgium
关键词
D O I
10.1016/j.jacc.2007.03.027
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A search of peer-reviewed literature was conducted to identify reports that provide data on complications associated with pregnancy in women with structural congenital heart disease (CHD). This review describes the outcome of 2,491 pregnancies, including 377 miscarriages (15%) and 114 elective abortions (5%). Important cardiac complications were seen in 11% of the pregnancies. Obstetric complications do not appear to be more prevalent. In complex CHD, premature delivery rates are high, and more children are small for gestational age. The offspring mortality was high throughout the spectrum and was related to the relatively high rate of premature delivery and recurrence of CHD.
引用
收藏
页码:2303 / 2311
页数:9
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