Iron overload in the liver diagnostic and quantification

被引：54

作者：

Alustiza, Jose M. ^{[1
]}

Castiella, Agustin ^{[1
]}

De Juan, Maria D. ^{[1
]}

Emparanza, Jose I. ^{[1
]}

Artetxe, Jose ^{[1
]}

Uranga, Maite ^{[1
]}

机构：

[1] Osatek SA, San Sebastian 20014, Guipuzcoa, Spain

来源：

EUROPEAN JOURNAL OF RADIOLOGY | 2007年 / 61卷 / 03期

关键词：

hemochromatosis; 761.659; liver biopsy 761.1261; liver diseases 761.659; magnetic resonance (MR) comparative studies 761.121411; 761.121412;

D O I：

10.1016/j.ejrad.2006.11.012

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Hereditary Hemochromatosis is the most frequent modality of iron overload. Since 1996 genetic tests have facilitated significantly the non-invasive diagnosis of the disease. There are however many cases of negative genetic tests that require confirmation by hepatic iron quantification which is traditionally performed by hepatic biopsy. There are many studies that have demonstrated the possibility of performing hepatic iron quantification with Magnetic Resonance. However, a consensus has not been reached yet regarding the technique or the possibility to reproduce the same method of calculus in different machines. This article reviews the state of the art of the question and delineates possible future lines to standardise this non-invasive method of hepatic iron quantification. (C) 2006 Elsevier Ireland Ltd. All rights reserved.

引用

页码：499 / 506

页数：8

共 33 条

[1] MR quantification of hepatic iron concentration [J].