Mass spectrometry of nucleotides and oligonucleotides

被引：8

作者：

Miketova, P ^{[1
]}

Schram, KH ^{[1
]}

机构：

[1] Univ Arizona, Coll Pharm, Dept Pharmacol & Toxicol, Tucson, AZ 85721 USA

来源：

MOLECULAR BIOTECHNOLOGY | 1997年 / 8卷 / 03期

关键词：

MALDI; ESI; mass spectrometry;

D O I：

10.1007/BF02760778

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent advances in the use of mass spectrometry for the determination of the molecular weight and sequencing of oligonucleotides are disscussed. Matrix-assisted laser desorption (MALDI) and electrospray ionization (ESI) mass spectrometry have been shown to be especially important techniques for both molecular weight assignment and sequencing of oligonucleotides, and are the focus of this article which covers the literature through early 1996.

引用

页码：249 / 253

页数：5

共 48 条

[1] ANTISENSE DNA OLIGONUCLEOTIDES .1. THE USE OF IONSPRAY TANDEM MASS-SPECTROMETRY FOR THE SEQUENCE VERIFICATION OF METHYLPHOSPHONATE OLIGODEOXYRIBONUCLEOTIDES [J].

BAKER, TR ;

KEOUGH, T ;

DOBSON, RLM ;

RILEY, TA ;

HASSELFIELD, JA ;

HESSELBERTH, PE .

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1993, 7 (03) :190-194

[2]

BARRY JP, 1995, J MASS SPECTROM, V30, P933

[3] 5S RIBOSOMAL-RNA MODIFICATION IN THE HYPERTHERMOPHILIC ARCHAEA SULFOLOBUS-SOLFATARICUS AND PYRODICTIUM-OCCULTUM [J].

BRUENGER, E ;

KOWALAK, JA ;

KUCHINO, Y ;

MCCLOSKEY, JA ;

MIZUSHIMA, H ;

STETTER, KO ;

CRAIN, PF .

FASEB JOURNAL, 1993, 7 (01) :196-200

[4] FOURIER-TRANSFORM MASS-SPECTROMETRY OF HIGH-MASS BIOMOLECULES [J].

BUCHANAN, MV ;

HETTICH, RL .

ANALYTICAL CHEMISTRY, 1993, 65 (05) :A245-&

[5] HIGH-RESOLUTION MATRIX-ASSISTED LASER-DESORPTION IONIZATION TIME-OF-FLIGHT ANALYSIS OF SINGLE-STRANDED-DNA OF 27 TO 68 NUCLEOTIDES IN LENGTH [J].

CHRISTIAN, NP ;

COLBY, SM ;

GIVER, E ;

HOUSTON, CT ;

ARNOLD, RJ ;

ELLINGTON, AD ;

REILLY, JP .

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1995, 9 (11) :1061-1066

[6] ANALYSIS OF OLIGODEOXYNUCLEOTIDES BY NEGATIVE-ION MATRIX-ASSISTED LASER-DESORPTION MASS-SPECTROMETRY [J].

CURRIE, GJ ;

YATES, JR .

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1993, 4 (12) :955-963

[7] ELECTROSPRAY IONIZATION FOR MASS-SPECTROMETRY OF LARGE BIOMOLECULES [J].

FENN, JB ;

MANN, M ;

MENG, CK ;

WONG, SF ;

WHITEHOUSE, CM .

SCIENCE, 1989, 246 (4926) :64-71

[8] BASIC MATRICES FOR THE MATRIX-ASSISTED LASER-DESORPTION IONIZATION MASS-SPECTROMETRY OF PROTEINS AND OLIGONUCLEOTIDES [J].

FITZGERALD, MC ;

PARR, GR ;

SMITH, LM .

ANALYTICAL CHEMISTRY, 1993, 65 (22) :3204-3211

[9] THE ANALYSIS OF MOCK DNA-SEQUENCING REACTIONS USING MATRIX-ASSISTED LASER-DESORPTION IONIZATION MASS-SPECTROMETRY [J].

FITZGERALD, MC ;

ZHU, L ;

SMITH, LM .

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 1993, 7 (10) :895-897

[10]

HATHAWAY GM, 1994, BIOTECHNIQUES, V17, P150

← 1 2 3 4 5 →