Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites

被引：619

作者：

Riggs, BL

Melton, LJ

Robb, RA

Camp, JJ

Atkinson, EJ

Peterson, JM

Rouleau, PA

McCollough, CH

Bouxsein, ML

Khosla, S

机构：

[1] Mayo Clin & Mayo Fdn, Endocrine Res Unit, Coll Med, Div Endocrinol & Metab,Dept Internal Med, Rochester, MN 55905 USA

[2] Mayo Clin & Mayo Fdn, Coll Med, Dept Hlth Sci Res, Rochester, MN 55905 USA

[3] Mayo Clin & Mayo Fdn, Dept Physiol & Biophys, Coll Med, Biomed Imaging Resource, Rochester, MN 55905 USA

[4] Mayo Clin & Mayo Fdn, Coll Med, Dept Radiol, Rochester, MN 55905 USA

[5] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Orthopaed Biomech Lab, Boston, MA 02115 USA

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2004年 / 19卷 / 12期

关键词：

osteoporosis; aging; menopause; bone densitometry; bone QCT; BMD; bone geometry;

D O I：

10.1359/JBMR.040916

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In a population-based, cross-sectional study, we assessed age- and sex-specific changes in bone structure by QCT. Over life, the cross-sectional area of the vertebrae and proximal femur increased by similar to15% in both sexes, whereas vBMD at these sites decreased by 39-55% and 34-46%, respectively, with greater decreases in women than in men.

引用

页码：1945 / 1954

页数：10

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