Mycobacterium marinum:: the generalization and specialization of a pathogenic mycobacterium

被引：53

作者：

Stamm, LA ^{[1
]}

Brown, EJ ^{[1
]}

机构：

[1] Univ Calif San Francisco, Program Host Pathogen Interact, San Francisco, CA 94158 USA

来源：

MICROBES AND INFECTION | 2004年 / 6卷 / 15期

关键词：

mycobacteria; macrophage; actin;

D O I：

10.1016/j.micinf.2004.10.003

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mycobacterium marinum is being used increasingly as a model for understanding pathogenic mycobacteria. However, recently discovered differences between M. marinum and M. tuberculosis suggest that adaptation to specialized niches is reflected in unique strategies of pathogenesis. This review emphasizes the areas in which studying M. marinum has made contributions to the understanding of tuberculosis, as well as the potential for using characteristics unique to M. marinum for understanding general issues of host-pathogen interactions. (C) 2004 Elsevier SAS. All rights reserved.

引用

页码：1418 / 1428

页数：11

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