Expression of the mouse Fkh1/Mf1 and Mfh1 genes in late gestation embryos is restricted to mesoderm derivatives

被引：39

作者：

Hiemisch, H

Monaghan, AP

Schütz, G

Kaestner, KH

机构：

[1] Univ Penn, Sch Med, Dept Genet, Philadelphia, PA 19104 USA

[2] German Canc Res Ctr, Div Mol Biol Cell 1, D-69120 Heidelberg, Germany

来源：

MECHANISMS OF DEVELOPMENT | 1998年 / 73卷 / 01期

关键词：

mouse embryo; Fkh1; Mfh1; Mf1; mesenchyme; cartilage primordia; nasal capsule; nasal septum; Meckel's cartilage; otic capsule; vertebra; winged helix transcription factors;

D O I：

10.1016/S0925-4773(98)00039-2

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We have compared the expression patterns of the mouse Forkhead homologue 1/ mesoderm/mesenchyme forkhead 1 (Fkh1/Mf1) gene with that of the highly related winged helix gene Mfh1 in late gestation mouse embryos. Transcripts for both genes are restricted to derivatives of the mesoderm. Go-expression was found in cartilage primordia of the head, ribs, vertebra and bones. However, in several structures analyzed, Fkh1/Mf1 signals are lower in the inner layers of the developing cartilage than those of Mfh1. (C) 1998 Elsevier Science Ireland Ltd.

引用

页码：129 / 132

页数：4

共 9 条

[1]

ANG SL, 1993, DEVELOPMENT, V119, P1301

[2]

Iida K, 1997, DEVELOPMENT, V124, P4627

[3] 6 MEMBERS OF THE MOUSE FORKHEAD GENE FAMILY ARE DEVELOPMENTALLY-REGULATED [J].