Gliding through sugar channels: how sweet it is!

被引:3
作者
Jap, BK [1 ]
Walian, PJ [1 ]
机构
[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Donner Lab, Div Life Sci, Berkeley, CA 94720 USA
关键词
D O I
10.1038/nsb0198-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The recently determined structures of ScrY and LamB porin, with and without bound ligands, have provided atomic-level details about the transit pathway of sugars through these channels and in turn revealed a novel transport mechanism.
引用
收藏
页码:6 / 8
页数:3
相关论文
共 9 条
  • [1] CRYSTAL-STRUCTURES EXPLAIN FUNCTIONAL-PROPERTIES OF 2 ESCHERICHIA-COLI PORINS
    COWAN, SW
    SCHIRMER, T
    RUMMEL, G
    STEIERT, M
    GHOSH, R
    PAUPTIT, RA
    JANSONIUS, JN
    ROSENBUSCH, JP
    [J]. NATURE, 1992, 358 (6389) : 727 - 733
  • [2] Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose
    Forst, D
    Welte, W
    Wacker, T
    Diederichs, K
    [J]. NATURE STRUCTURAL BIOLOGY, 1998, 5 (01) : 37 - 46
  • [3] Structure and functional mechanism of porins
    Jap, BK
    Walian, PJ
    [J]. PHYSIOLOGICAL REVIEWS, 1996, 76 (04) : 1073 - 1088
  • [4] Structure of maltoporin from Salmonella typhimurium ligated with a nitrophenyl-maltotrioside
    Meyer, JEW
    Hofnung, M
    Schulz, GE
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1997, 266 (04) : 761 - 775
  • [5] NIKAIDO H, 1985, MICROBIOL REV, V49, P1
  • [6] TRANSPORT PROTEINS IN BACTERIA - COMMON THEMES IN THEIR DESIGN
    NIKAIDO, H
    SAIER, MH
    [J]. SCIENCE, 1992, 258 (5084) : 936 - 942
  • [7] STRUCTURAL BASIS FOR SUGAR TRANSLOCATION THROUGH MALTOPORIN CHANNELS AT 3.1-ANGSTROM RESOLUTION
    SCHIRMER, T
    KELLER, TA
    WANG, YF
    ROSENBUSCH, JP
    [J]. SCIENCE, 1995, 267 (5197) : 512 - 514
  • [8] Channel specificity: Structural basis for sugar discrimination and differential flux rates in maltoporin
    Wang, YF
    Dutzler, R
    Rizkallah, PJ
    Rosenbusch, JP
    Schirmer, T
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1997, 272 (01) : 56 - 63
  • [9] STRUCTURE OF PORIN REFINED AT 1.8 ANGSTROM RESOLUTION
    WEISS, MS
    SCHULZ, GE
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1992, 227 (02) : 493 - 509