Antimicrobial and radical scavenging flavonoids from the stem wood of Erythrina latissima

被引：80

作者：

Chacha, M ^{[1
]}

Bojase-Moleta, G ^{[1
]}

Majinda, RRT ^{[1
]}

机构：

[1] Univ Botswana, Dept Chem, Gaborone, Botswana

来源：

PHYTOCHEMISTRY | 2005年 / 66卷 / 01期

关键词：

Erythrina latissima; Fabaceae-Papilionoideae; isoflavones; flavanone; erylatissins A-C; antibacterial; antifungal activity; radical scavenging properties;

D O I：

10.1016/j.phytochem.2004.10.013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

From the stem wood of Erythrina latissima, two isoflavones and a flavanone were isolated and characterized as 7,3'-dihydroxy-4'-methoxy-5'-(gamma,gamma-dimethylallyl)isoflavone (erylatissin A), 7,3'-dihydroxy-6",6"-dimethyl-4",5"-dehydropyrano [2", 3": 4' ,5']isoflavone (erylatissin B), (-)-7,3'-dihydroxy-4'-methoxy-5'-(gamma,gamma-dimethylallyl)flavanone (erylatissin C), respectively, in addition to 10 known flavonoids. Structures of these compounds were determined on the basis of their spectroscopic data. These compounds showed antimicrobial activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Candida mycoderma. The isolated compounds also exhibited weak radical scavenging properties towards DPPH radical. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：99 / 104

页数：6

共 28 条

[1] Isoprenylated flavonoids from hairy root cultures of Glycyrrhiza glabra [J].