Serotonin syndrome and other serotonergic disorders

被引：107

作者：

Ener, RA

Meglathery, SB

Decker, WAV

Gallagher, RM

机构：

[1] MCP Hahnemann Univ Hosp, Philadelphia, PA 19102 USA

[2] Drexel Univ, Coll Med, Philadelphia, PA 19104 USA

来源：

PAIN MEDICINE | 2003年 / 4卷 / 01期

关键词：

serotonin syndrome; neuroleptic malignant syndrome (NMS); akathisia; tardive dyskinesia; parkinson's disease; selective serotonin reuptake inhibitors (SSRI); neuroleptics;

D O I：

10.1046/j.1526-4637.2003.03005.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Serotonin syndrome is an iatrogenic disorder induced by pharmacologic treatment with serotonergic agents that increases serotonin activity. In addition, there is a wide variety of clinical disorders associated with serotonin excess. The frequent concurrent use of serotonergic and neuroleptic drugs and similarities between serotonin syndrome and neuroleptic malignant syndrome can present the clinician with a diagnostic challenge. In this article, we review the pathophysiology, diagnosis, and treatment of serotonin syndrome as well as other serotonergic disorders.

引用

页码：63 / 74

页数：12

共 53 条

[1] Nonfunctional CYP2D6 alleles and risk for neuroleptics-induced movement disorders in schizophrenic patients [J].