Dermatomyositis associated with the presence of parvovirus B19 DNA in muscle

被引：48

作者：

Chevrel, G

Calvet, A

Belin, V

Miossec, P

机构：

[1] Hop Edouard Herriot, Dept Immunol & Rheumatol, F-69437 Lyon 03, France

[2] Dept Virol, Lyon, France

来源：

RHEUMATOLOGY | 2000年 / 39卷 / 09期

关键词：

dermatomyositis; autoimmune disease; parvovirus B19; muscle biopsy; polymerase; chain reaction;

D O I：

10.1093/rheumatology/39.9.1037

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of dermatomyositis associated with molecular evidence of parvovirus B19 DNA in two muscle biopsies collected 5 months apart. IgG- but not IgM-specific antibodies were detected in serum. None of four serum samples was positive for parvovirus B19 DNA. The two biopsies contained B19 VPI sequences and the second one was also positive for NS1. This is the first report of viral parvovirus B19 DNA in muscle of a patient with dermatomyositis. Latent muscle infection may contribute to the clinical picture.

引用

页码：1037 / 1039

页数：3