Immune response to early and late Histoplasma capsulatum infections

被引:35
作者
Deepe, GS [1 ]
机构
[1] Univ Cincinnati, Coll Med, Dept Med, Div Infect Dis, Cincinnati, OH 45267 USA
关键词
D O I
10.1016/S1369-5274(00)00104-1
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Knowledge of the host response to the intracellular pathogenic fungus Histoplasma capsulatum has increased dramatically. Information has accumulated regarding the cellular and molecular determinants that lead to resolution of both primary and secondary infection. The significance of cytokines and other endogenous soluble mediators to the protective immune response have been analyzed. Moreover, work concerning the relative importance of T cell subsets to protective immunity has been initiated.
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收藏
页码:359 / 362
页数:4
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