Fingers reach for the genome

被引：10

作者：

Ansari, AZ ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Biochem, Madison, WI 53706 USA

来源：

NATURE BIOTECHNOLOGY | 2003年 / 21卷 / 03期

关键词：

D O I：

10.1038/nbt0303-242

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

Two new approaches promise to facilitate the identification of zinc fingers that function optimally in vivo.

引用

页码：242 / 243

页数：2

共 11 条

[1]

Modular design of artificial transcription factors [J].

Ansari, AZ ;

Mapp, AK .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2002, 6 (06) :765-772

[2]

Human zinc fingers as building blocks in the construction of artificial transcription factors [J].

Bae, KH ;

Do Kwon, Y ;

Shin, HC ;

Hwang, MS ;

Ryu, EH ;

Park, KS ;

Yang, HY ;

Lee, D ;

Lee, Y ;

Park, J ;

Kwon, HS ;

Kim, HW ;

Yeh, BI ;

Lee, HW ;

Sohn, SH ;

Yoon, J ;

Seol, W ;

Kim, JS .

NATURE BIOTECHNOLOGY, 2003, 21 (03) :275-280

[3]

Engineering polydactyl zinc-finger transcription factors [J].

Beerli, RR ;

Barbas, CF .

NATURE BIOTECHNOLOGY, 2002, 20 (02) :135-141

[4]

Scanning the human genome with combinatorial transcription factor libraries [J].

Blancafort, P ;

Magnenat, L ;

Barbas, CF .

NATURE BIOTECHNOLOGY, 2003, 21 (03) :269-274

[5]

Correction of disease-associated exon skipping by synthetic exon-specific activators [J].

Cartegni, L ;

Krainer, AR .

NATURE STRUCTURAL BIOLOGY, 2003, 10 (02) :120-125

[6]

CHENG X, 1994, P NATL ACAD SCI USA, V94, P14120

[7]

TOWARD RULES RELATING ZINC FINGER PROTEIN SEQUENCES AND DNA-BINDING SITE PREFERENCES [J].

DESJARLAIS, JR ;

BERG, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (16) :7345-7349

[8]

Specific RNA binding proteins constructed from zinc fingers [J].

Friesen, WJ ;

Darby, MK .

NATURE STRUCTURAL BIOLOGY, 1998, 5 (07) :543-546

[9]

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions - Activation of vascular endothelial growth factor A [J].

Liu, PQ ;

Rebar, EJ ;

Zhang, L ;

Liu, Q ;

Jamieson, AC ;

Liang, YX ;

Qi, H ;

Li, PX ;

Chen, BL ;

Mendel, MC ;

Zhong, XH ;

Lee, YL ;

Eisenberg, SP ;

Spratt, SK ;

Case, CC ;

Wolffe, AP .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (14) :11323-11334

[10]

REPETITIVE ZINC-BINDING DOMAINS IN THE PROTEIN TRANSCRIPTION FACTOR IIIA FROM XENOPUS OOCYTES [J].

MILLER, J ;

MCLACHLAN, AD ;

KLUG, A .

EMBO JOURNAL, 1985, 4 (06) :1609-1614

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